Target List
TGFβ Signaling
ACTC1ATF4BMPR2CDKN1BEGR2EMP1FASFGF2FSTL3GADD45BHERPUD1IFRD1JUNBKANK4KLHL24MYCCCN3PMEPA1SERPINE1SMAD6SOX4STK38LTNFSF10UBASH3B
WNT Signaling
AXIN2BOD1CALM1CCND1CCND2CHSY1CXADRCYP4V2DAB2FOSL1HSPA12ALEF1MMP7MT1AMTFP1MTSS1MYCNAV2PPARDPRMT6SKP2CCN4
NFκB Signaling
BCL2A1BCL2L1BCL2L1BCL2L1BIRC3CCL20CCL5CD83CSF1CXCL2CXCL3CXCL8ICAM1IFNGIRF1NFKB1NFKBIANFKBIESTAT1STX11TIFATNFTNFAIP2TNFAIP3
JAK/STAT Signaling
A2MBCL2L1BCL2L1BCL2L1BIRC5CCL11CCND1CDKN1ACSN2CXCL9FCER2GATA3HPICAM1IFNGIL10IL21IRF1IRF8ISG15MCL1MMP2NOS2OAS1SOCS3TAP1
p53 Signaling
BAXBBC3BTG2CCNG1CDKN1ACYFIP2EGFRFASFOSGADD45AGDF15IGFBP3MMP2MSH2PCNAPIDD1PMAIP1PTENRB1RNF144BRRM2BSESN1SFNTNFRSF10BTP53I3TP53INP1
Notch Signaling
ADAAFAP1L2DTX1H19HES1Hes4HES5HEY1HEY2HEYLID1JAG1LFNGNOTCH1NRARPSCGB1A1SERPINA3SLC6A12SNAI2TFF1TNFSF10UBD
Hedgehog Signaling
BCL2BMP2BMP4CCND1CCND2CDH1FSTGLI1GLI2GLI3HHIPIFITM5MUC5ACPTCH1SNAI1SOX2WNT1WNT2BWNT3AWNT5AWNT6
PPAR Signaling
ACSL3ACSL4ACSL5APOA1APOA5APOC3APOECPT2DGAT1FABP1FABP3FABP4GKHIF1AHMGCS2MMP9NR1H3OLR1PCK1PCK2PLTPPTENSLC27A1SLC27A4SORBS1TXNIP
Oxidative Stress Response
AKR1C2BAG2FHL2FTH1GCLCGCLMGLAGSRHMOX1HSP90AA1LHPPNCOA7NQO1PTGR1SLC7A11SPINK1SQSTM1TRAPPC6ATXNTXNRD1
Hypoxia Response
ADMALDOCANGPTL4ANKRD37ARNTBHLHE40BNIP3BNIP3LCA9EPOFAM162AHK2HMOX1LDHANDRG1P4HA1PFKFB4PGK1SERPINE1SLC2A1SLC2A3VEGFA
Insulin Signaling
ACACAADIPOQBCL2L1BCL2L1BCL2L1CEBPACEBPBFABP4FASNFOSFOXO1G6PCGCKIGFBP1INSRIRS1JUNLEPNOS2NPYPPARGSERPINE1SLC2A1SLC2A4SREBF1VEGFA
MAPK Signaling
ALAS1ATF3BCL2BDNFCCKCCL2CCNA2CCND1CDC25ACDKN1ACIITACKMDDIT3DIO2DUSP1EGR1HSPA5IL1BIL6MMP13NR4A1NR4A2PRKCAPTGS2RENSLC19A1SSTTLR9
PI3K-AKT Signaling
ARBBC3BCL2L11BIRC5BNIP3CCNG2CDKN1BCYP7A1ESR1FASLGFBXO32IGFBP1IRS2KLF2MYOCDNOS3PDX1PPARGC1APRDX3PRLRICTORSOD2TGFB2TNFRSF1B
DNA Damage Response
APEX1ATMBRCA1DDB2ERCC1ERCC2EXO1FEN1LIG1MLH1MSH2OGG1PARP1PMS2PNKPPRKDCRAD50RAD51RPA1TP53UNGXPAXPCXRCC1XRCC6
Estrogen Signaling
ABCG2ADORA1BCL2C3CA12CCND1CYP19A1CYP1A1F12FSTGREB1IGF1IGFBP4MYCPGRPRLRAP1GAPRARARETSGK3TFF1TNF
Androgen Signaling
ABCC4ADCYAP1CAMKK2DBIDHCR24FKBP5GUCY1A1IGF1IGF1RIGFBP3IGFBP5KLK2KLK3MMEMYCNDRG1NKX3-1PGCPMEPA1SLC45A3SNAI2STK39TMPRSS2TPD52ZBTB16
Glucocorticoid Signaling
ANGPTL4BCL6CEBPBDUSP1EDN1FKBP5FOSL2HTR1AIL6KLF9MT2ANFKBIAPCK1PCK2PER1PER2RHOBSCNN1ASGK1SLC19A2SLC22A5TATTNFAIP3TSC22D3ZFP36ZNF281
MYC Targets
APEX1CADCCT5CDK4CDKN1BCDKN2BCSDE1DKC1ENO1HNRNPA1ID3ILKITGB1MYCNAP1L1NCLNME1NPM1PA2G4PPATPTPAPSMG1SRSF1TERTUBE2CYBX3ZFP36L1
Retinoic Acid Signaling
BHLHE40CDX1CRABP1CRABP2CYP26A1CYP26B1CYP26C1DHRS9EGR1GBX2HNF1BHOXA1HOXB1LEFTY1RARARARBRARGRBP1RBP4STRA6TGM2
Unfolded Protein Response
ADM2ASNSBEX2DDIT3DNAJB9GINS2HERPUD1INHBEKCNMB3MCM4PCNARRM2SLC17A2TRIB3TYMSUHRF1