Target List
Angiogenesis
ANGPT1CCL2 (MCP-1)CCL5 (RANTES)CX3CL1EDN1EDNRAENG (EVI-1)F3FASLG (TNFSF6)FGF1FGF2 (BFGF)FLT1 (VEGFR1)FN1HIF1AHMOX1IL1BIL6ITGA5ITGAVITGB1ITGB3KDR (VEGFR3)KIT (CD117)KLK3MMP2MMP9NOS3 (eNOS)NPPBNPR1PF4PGFPLAU (UPA)PTGS2 (COX2)SERPINE1 (PAI-1)SPHK1TEK (TIE-2, TIE2)THBS1 (TSP-1)TYMPVEGFA
Vasoconstriction & Vasodilation
ACEAGTAGTR1ALOX5APOECALCACAV1CX3CL1EDN1EDN2EDNRAF2R (PAR1)HMOX1ICAM1NOS3 (eNOS)NPPBNPR1PTGISPTGS2 (COX2)SOD1
Inflammatory Response
ACEAGTAGTR1ALOX5APOECALCACCL2 (MCP-1)CCL5 (RANTES)CX3CL1EDNRAF2R (PAR1)F3FN1HIF1AHMOX1IL1BIL6NPPBPTGS2 (COX2)SELESPHK1TGFB1THBS1 (TSP-1)TNFVCAM1
Apoptosis
ANXA5BAXBCL2BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)CASP1 (ICE)CASP3CAV1CCL2 (MCP-1)CCL5 (RANTES)CFLAR (CASPER)CX3CL1EDN1EDNRAFASFASLG (TNFSF6)FGF2 (BFGF)HIF1AHMOX1IL1BIL3IL6IL7OCLNPF4PTK2 (FAK)SPHK1TEK (TIE-2, TIE2)THBS1 (TSP-1)TNFTNFSF10 (TRAIL)
Cell Adhesion Molecules
ADAM17 (CD156B)AGTBCL2CALCACDH5COL18A1CX3CL1ENG (EVI-1)FGF1FN1ICAM1IL1BITGA5ITGAVITGB1ITGB3KDR (VEGFR3)PDGFRAPECAM1PLAU (UPA)PLGPTK2 (FAK)SELESELL (LECAM-1)SELPLG (P-Selectin)SERPINE1 (PAI-1)TGFB1THBS1 (TSP-1)TNFVCAM1VEGFAVWF
Coagulation
ANXA5CAV1EDN1F2R (PAR1)F3FN1MMP1PECAM1PF4PLAT (TPA)PLAU (UPA)PLGPROCR (EPCR)PTK2 (FAK)SELL (LECAM-1)SELPLG (P-Selectin)SERPINE1 (PAI-1)TEK (TIE-2, TIE2)TFPITHBDTHBS1 (TSP-1)TIMP1VWF
Platelet Activation
APOECX3CL1F2R (PAR1)FN1IL11IL6ITGB3NOS3 (eNOS)PDGFRAPECAM1PF4PLGSERPINE1 (PAI-1)SOD1TGFB1THBDTHBS1 (TSP-1)TIMP1VEGFAVWF