Target List
Th2 Cytokines & Related Genes
AREGCCL11 (Eotaxin)CCL17 (TARC)CCL2 (MCP-1)CCL22 (MDC)CCL24 (MPIF-2, Eotaxin-2)CCL26 (Eotaxin-3)CCL5 (RANTES)CCL8 (MCP-2)CLCCSF2 (GM-CSF)PTGDR2 (CRTH2, GPR44)ICOSIFNGIL10IL12AIL12BIL13IL17AIL18IL21IL25IL3IL31IL33IL4IL5IL9PDCD1 (PD1)PDCD1 (PD1)PMCHTGFB1TNFSF4 (OX40L)TSLP
Cytokine & Chemokine Receptors
CCR3CCR4CCR8CD40LGCRLF2 (TSLPR)CSF3R (GM-CSFR)IFNGR2IL13RA1IL13RA2IL17RBIL1RL1 (ST2)IL2RA (CD25)IL3RAIL4R (CD124)IL5RA (CD125)TNFRSF4 (OX40)
Transcription Factors
BCL6FOXP3GATA3MAFPPARGRORCSATB1STAT5ASTAT6TBX21
Mast Cells & IgE
CMA1CPA3FCER1AKIT (CD117)KITLG (SCF)KITLG (SCF)MS4A2TPSAB1
Eosinophils
EPXPRG2RNASE2RNASE3SIGLEC8
Natural Killer (NK) Cells
IFNGIL12AIL12BIL13IL18IL21IL33
Alternatively Activated Macrophages
ARG1CHI3L1CHIAMRC1RETNLB
Asthma
ADAM33ADRB2ALOX5CLCA1CYSLTR1LTB4RMMP9POSTN