Target List
G-Protein Coupled Receptors (GPCRs)
Bioactive Lipid Receptors
LPAR1LPAR2S1PR1S1PR2S1PR3
Metabotropic Glutamate & GABA-Like Receptors
CASRGRM1GRM2GRM4GRM5GRM7
Rhodopsin-Like Receptors
ADORA2AADRB1ADRB2AGTR1AGTR2AGTRAPDRD1DRD2GALR2LHCGRLPAR1LPAR2OPRD1OPRK1PTGDRRHOS1PR1S1PR2S1PR3TSHR
Secretin-Like Receptors
ADGRB1 (BAI1)ADORA2ACALCRCALCRLCRHR1CRHR2GCGRPTH1RSCTR
Other G-Protein Coupled Receptors (GPCRs)
EDN1
G-Protein Coupled Receptor Signaling Pathways
Dopamine Receptor Signaling
DRD1DRD2OPRD1
G-Protein & cAMP / Protein Kinase A Signaling
ADCY5ADORA2AADRB1ADRB2CALCRCALCRLCCL2 (MCP-1)COL1A1CRHR1CRHR2CYP19A1DRD1EDN1GALR2GCGRGNAQGNASGRM2GRM4IL1R1IL1R2LHCGRNOS2 (iNOS)OPRD1OPRK1PTGS2 (COX2)PTH1RRGS2S1PR1S1PR3TSHRUCP1VEGFA
G-Protein & IP3 / Phospholipase C Signaling
AGTR1CALCRCASREDN1GNAQGRM5LPAR1LPAR2PIK3CG
Metabotropic Glutamate Receptor Signaling
GRM1GRM2GRM4GRM5GRM7
Neuropeptide Signaling
ADGRB1 (BAI1)OPRD1
Adenosine Receptor Signaling
ADCY5ADORA2A
Calcium Signaling (PKC, NFAT, etc.)
CCL2 (MCP-1)CCL4 (MIP-1B)COL1A1EGR1ELK1ELK4PTGS2 (COX2)
PKC Signaling (Calcium, MEK, etc.)
AGTR2COL1A1DUSP14EGR1FGF2 (BFGF)FOSIL1R1IL1R2JUNJUNBMMP9MYCNOS2 (iNOS)PRKCAPTGS2 (COX2)RGS2SERPINE1 (PAI-1)SOCS1
Tyrosine Kinase Signaling
ADRB2AKT1CCL4 (MIP-1B)CCN2PDPK1PRKCARGS2SOCS1YWHAZ
Protein Serine / Threonine Kinase Signaling
AKT1CDKN1B (P27KIP1)PDPK1PTGDR
MAP Kinase Signaling
ADRB2AGTFGF2 (BFGF)GRM1GRM4PRKCAS1PR2TNFUCP1
PI3 Kinase Signaling
AKT1BCL2BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)CCND1CDKN1B (P27KIP1)CFLAR (CASPER)PDPK1PIK3CGPTGS2 (COX2)
Nitric Oxide / cGMP Signaling
AGTR2NOS2 (iNOS)PTGS2 (COX2)TNF
RHO Signaling
CCN2CDKN1B (P27KIP1)FOSIL1BPTGS2 (COX2)RHOSERPINE1 (PAI-1)
IκB Kinase / NFκB Cascade
AGTCFLAR (CASPER)ICAM1IL1BIL2LPAR1MAXNOS2 (iNOS)PTGS2 (COX2)TNFVCAM1
JAK / STAT Signaling
CCL2 (MCP-1)CDKN1A (p21CIP1, WAF1)SOCS1
Other G-Protein Coupled Receptor Signaling Pathways
ARRB1ARRB2CCNE1CCNE2