Target List
Ubiquitin-Activating Enzymes (E1)
ATG7MOCS3NAE1NEDD8SAE1UBA1UBA2UBA3UBA5UBA6UBE2Z
Ubiquitin-Conjugating Enzymes (E2)
Regulation of Apoptosis
BARD1BRCA1TP53 (p53)UBE2Z
Cell Cycle Regulators
ANAPC2BARD1BRCA1CDC34TP53 (p53)UBE2CUBE2I
Transcriptional Regulation
BRCA1TP53 (p53)UBE2KUBE2W
Other Ubiquitin-Conjugating Enzymes (E2)
ARIH1BTRC (bTrCP)NEDD8PRKNSTUB1TMEM189UBA6UBE2AUBE2BUBE2D1UBE2D2UBE2D3UBE2E1UBE2E2UBE2E3UBE2G1UBE2G2UBE2HUBE2J1UBE2J2UBE2L3UBE2MUBE2NUBE2Q1UBE2R2UBE2SUBE2TUBR2
Ubiquitin-Protein Ligases (E3)
Regulation of Apoptosis
BARD1BRCA1CUL1CUL2CUL3CUL4ACUL5TP53 (p53)UBE4BVHL
Cell Cycle Regulators
ANAPC11ANAPC2BARD1BRCA1CUL1CUL2CUL3CUL4ACUL4BCUL5CUL7CUL9DDB1MDM2SKP1SKP2TP53 (p53)VHL
Transcriptional Regulation
BRCA1CBLMDM2SMURF2TP53 (p53)VHLWWP1
Other Ubiquitin-Protein Ligases (E3)
ARIH1BRCC3BTRC (bTrCP)COP1DZIP3FBXO3FBXO31FBXO4FBXW10FBXW9HECW1HECW2HERC5HUWE1MARCH5MIB1MUL1NEDD8PRKNRNF123RNF148SMURF1STUB1SYVN1UBE2L3UBE2TUBR1UBR2