Target List
Chemotaxis
FGF2 (BFGF)ITGB2MAPK1 (ERK2)MYH10MYH9PLAUR (UPAR)PLD1PRKCARAC2TGFB1VEGFAWASF2WIPF1
Receptors
EGFR (ERBB1)IGF1RITGA4 (CD49D)ITGB1ITGB2ITGB3METPLAUR (UPAR)RHO
Growth Factors
CSF1 (MCSF)EGFFGF2 (BFGF)HGFIGF1TGFB1VEGFA
Rho Family GTPases
RHO Signaling
ACTR2ACTR3ARHGDIALIMK1MSNMYL9MYLKPLCG1PLD1PRKCAPTENPTPN1 (PTP1B)RHORHOARHOBRHOCRND3ROCK1VIM
RAC Signaling
ACTR2ACTR3BAIAP2CFL1CRKPAK1PAK4PLD1PRKCARAC1RAC2STAT3WASF1WASF2WASL
CDC42 Signaling
ACTR2ACTR3CDC42PFN1WASF1WASF2WASL
Cell Adhesion Molecules
Cell-Cell Adhesion
DPP4EGFR (ERBB1)EZRITGA4 (CD49D)ITGB1ITGB2MSNMYH9ROCK1TGFB1
Cell-Extracellular Matrix (ECM) Adhesion
ACTN1ACTN3CSF1 (MCSF)ILKITGB1ITGB2ITGB3MMP14PTENPTK2B (PYK2)PXNRASA1RHOA
Focal Adhesions
ACTN1ACTN3ARHGEF7BCAR1CAPN1CAPN2CAV1ENAHILKITGB1MYL9PTK2 (FAK)PTK2B (PYK2)PXNTLN1VASPVCL
Leukocyte Adhesion & Rolling
EZRITGA4 (CD49D)ITGB1ITGB2MSNROCK1
Integrin Signaling
BCAR1ILKITGA4 (CD49D)ITGB1ITGB2ITGB3MYH9PTK2 (FAK)
Cellular Projections
Filopodia
BAIAP2CDC42DIAPH1EGFR (ERBB1)ENAHEZRMSNRDXSVILVASP
Lamellipodia
CTTNDPP4EGFR (ERBB1)ENAHFAPPIK3CA (p110-alpha)PLD1PTK2 (FAK)PXNRDXSVILVASPVCLWASF1WASF2WASL
Stress Fibers
ACTN4DIAPH1MYH10MYH9RHOARHOBRHOC
Membrane Blebs
ACTN1ACTN3ACTN4EZRMYH10MYH9MYLKRND3ROCK1
Invasive Projections
ACTR2ACTR3ARF6CDC42CFL1CTTNDPP4EGFEZRFAPMMP14MMP2MMP9MSNMYH9PLAUR (UPAR)RAC2RASA1SH3PXD2ASRCSVILTGFB1VEGFAWASLWIPF1
Growth Cones
ARHGEF7CDC42CFL1PTK2B (PYK2)
Membrane Ruffles
ACTR2ACTR3ARF6BAIAP2BCAR1CTTNDIAPH1EZRITGB1MYH9RAC1RAC2RDXRHOATLN1WASF2
Cell Polarity
CDC42CFL1EZRIGF1RILKMYH9
Proteases & Protease Inhibitors
AKT1CAPN1CAPN2DPP4FAPHGFMMP14MMP2MMP9MYH9PLAUR (UPAR)TIMP2