Target List
Apoptosis
CASP1 (ICE)CCL2 (MCP-1)EGR3IL1BIL2RA (CD25)IL6ITGB2LCN2 (NGAL)SOD2TNF
Inflammation
C3CCL11 (Eotaxin)CCL2 (MCP-1)CCL20 (MIP-3A)CCL25 (TECK)CCL5 (RANTES)CCR1CCR2CCR5CX3CL1CXCL1 (GRO1, GROa, SCYB1)CXCL10 (INP10)CXCL11 (I-TAC, IP-9)CXCL2 (GRO2, GROb, SCYB2)CXCL3CXCL9 (MIG)CXCR1FPR1IL13IL17AIL1BIL2RA (CD25)IL23AIL5IL6CXCL8 (IL8)ITGB2LTBLYZS100A8S100A9SAA1SELESTAT3TNF
Immunity
Humoral Immunity
CCL2 (MCP-1)IL6DEFA5DEFA6LYZ
Innate Immunity
C3C4BPBCASP1 (ICE)CD55CR2IL1RNIRF5ISG15LCN2 (NGAL)NOD2NOS2 (iNOS)SAA1TYK2
Adaptive Immunity
CCL11 (Eotaxin)CCR2CCR5CCR9CXCR3HLA-DQA1HLA-DRAHLA-DRB1IFNGIL13IL17AIL2RA (CD25)IL5IL6IRF5STAT1
Extracellular Matrix (ECM) & Cell Adhesion Molecules
CCL2 (MCP-1)CCR1CCL11 (Eotaxin)CSTACX3CR1CXCL12 (SDF1)CXCR3ITGB2MMP1MMP10MMP3MMP7PECAM1SELESELL (LECAM-1)TIMP1VWF
Unfolded Protein Response
HSP90B1HSPA5 (GRP78)UBD
Digestive Secreted Proteins
GCGMUC1 (mucin)REG1AREG1BTFF1 (pS2)
Metabolism
ALDOBPCK1TDO2
Other Crohn's Disease Genes
ABCB1 (MDR1, PGY1)ATG16L1CHI3L1EDN3NR3C2