Target List
Apoptosis
Pro-Apoptotic
ABL1APAF1ATP6V1G2BAXBCL2L11BIRC2 (c-IAP1)CASP1 (ICE)CASP3CASP6CASP7CASP9CD40 (TNFRSF5)CD40LGCFLAR (CASPER)CYLDDFFAFASFASLG (TNFSF6)GADD45ANOL3SPATA2SYCP2TNFTNFRSF10A (TRAIL-R)TNFRSF1A (TNFR1)TP53 (p53)
Anti-Apoptotic
AKT1BCL2BCL2A1 (BFL1)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BIRC3 (c-IAP2)CASP2IGF1RMCL1TNFRSF11B (OPG)TRAF2XIAP
Autophagy
AKT1APPATG12ATG16L1ATG3ATG5ATG7BAXBCL2BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BECN1CASP3CTSBCTSSESR1 (ERα)FASGAAHTTIFNGIGF1INSIRGMMAP1LC3AMAPK8 (JNK1)NFKB1PIK3C3 (VPS34)RPS6KB1SNCASQSTM1TNFTP53 (p53)ULK1
Necrosis
ATP6V1G2BMFC1orf159CCDC103COMMD4CYLDDEFB1DENND4ADPYSL4EIF5BFOXI1GALNT5GRB2HSPBAP1JPH3KCNIP1MACO1MAGOR10J3PARP1 (ADPRT1)PARP2PVRRAB25S100A7ASPATA2SYCP2TNFRSF1A (TNFR1)TXNL4B