Target List
Drug Transporters
Metallothioneins
Mt3
P-Glycoprotein Family Members
Abcb1a (Mdr1)Abcc1 (Mrp1)Abcc2 (Cmoat, Mrp2)Abcc3 (Mlp2, Mrp3)Gpi
Phase I Metabolizing Enzymes
Cytochrome P450s
Cyp17a1Cyp19a1Cyp1a1Cyp1a2Cyp1b1Cyp27b1Cyp2b15Cyp2b3Cyp2c13Cyp2c6v1Cyp2c7Cyp2e1Cyp3a18Cyp4b1
Phase II Metabolizing Enzymes
Carboxylesterases
Ces1aCes2c (QuantiNova Symbol: LOC100365112)
Decarboxylases
Gad1Gad2
Dehydrogenases
Adh1Adh4AladAldh1a1Hsd17b1Hsd17b2Hsd17b3
Glutathione Peroxidases (GPx)
Gpx1Gpx2Gpx3Gpx4Gpx5Gsta1Gsta4Gstm1 (Mgst1)Gstm2Gstm3Gstm4Gstm5 (QuantiNova Symbol: Gstm3l)Gstp1Gstt1LpoMpo
Hydrolases
Ephx1FaahFbp1
Kinases
Hk2PklrPkm
Lipoxygenases
Alox15Alox5Apoe
Oxidoreductases
BlvraBlvrbCyb5r3Gpx1Gpx2GsrMthfrNos2 (Nos2a, iNos)Nos3 (eNOS)Nqo1Srd5a1Xdh (Srd5a2)
Paraoxonases
Pon1Pon2Pon3
Glutathione S-Transferases
Chst1Gsta1Gstm2Gstm3Gstm5 (QuantiNova Symbol: Gstm3l)Gstp1Gstt1Mgst1Mgst2Mgst3
Transferases
Nat1
Other Phase II Metabolizing Enzymes
ComtGgt1
Other Drug Metabolism Genes
AhrAoc1ArntAsna1GckrMarcksSmarcal1Snn