Target List
G1 Phase & G1/S Transition
Cdk6Cdkn3Gpr132Itgb1Nfatc1Skp2Slfn1 (QuantiNova Symbol: AC128859.3)
S Phase & DNA Replication
Cdc6Cdc7Mcm2Mcm3Mcm4Mki67Mre11aMsh2Rad17Rad51
G2 Phase & G2/M Transition
Birc5Cdkn3Ppm1d (Wip1)Stt3a
M Phase
AurkbBrca2Ccna1Ccnb1Cdc20Cdc25aCdc25bCdc25cCdc6Cdk1Cdk2Nek2Rad21RanShc1Smc1aStag1Stmn1Terf1Wee1
Cell Cycle Checkpoint & Cell Cycle Arrest
Brca2Casp3Cdc25cCdk1Cdk5rap1Cdkn1a (Cip1, Waf1)Cdkn1b (P27KIP1)Cdkn2a (INK4A, p16, p19ARF)Cdkn2b (p15)Cdkn3Chek2Ddit3 (Gadd153, Chop)DstGadd45aHus1InhaMad2l1Mdm2Msh2Nbn (Nbs1)Notch2Pkd1Pmp22Ppm1d (Wip1)Rad9a (Rad9)Rb1Sesn2Sfn (14-3-3σ)Slfn1 (QuantiNova Symbol: AC128859.3)Smc1aStt3aTsg101
Regulation of the Cell Cycle
AurkaBcl2Brca2Ccna1Ccna2Ccnb1Ccnb3CcncCcnd1Ccnd2Ccnd3Ccne1CcnfCdc20Cdc25cCdc6Cdk1Cdk4Cdk6Cdkn1a (Cip1, Waf1)E2f1E2f3E2f4Gadd45aItgb1LOC100909750 (Abl1)Rad9a (Rad9)RanRb1Sfn (14-3-3σ)Shc1Skp2Tfdp2
Negative Regulation of the Cell Cycle
AtmBrca1Casp3Cdkn2a (INK4A, p16, p19ARF)InhaRbl1Rbl2Tp53 (p53)Tp63