Target List
ATM / ATR Signaling
AtmBard1Brca1Cdc25aChek2Csnk2a2Fancd2Hus1Parp1 (Adprt1)Parp2Rad1Rad17Rad50Rad9a (Rad9)Rnf8Smc1aTopbp1Tp53 (p53)
DNA Damage & Repair
Nucleotide Excision Repair (NER)
Brca2Dclre1aDdb2Ercc1Ercc2 (Xpd)FanccLig1Nthl1Ogg1PcnaPold3PoleRpa1Sirt1 (QuantiNova Symbol: AABR07044925.1)Tp53 (p53)Xpc
Base Excision Repair (BER)
Apex1Fen1Lig1Mbd4MpgNthl1Ogg1Parp1 (Adprt1)Parp2PcnaPoleTp53 (p53)UngWrnXrcc1
Mismatch Repair (MMR)
Exo1LOC100909750 (Abl1)Mlh1Mlh3Msh2Msh3PcnaPms1Pms2
Double-Strand Break (DSB) Repair
AtmBlmBrca1Brca2Hus1Lig1Mlh1Mre11aNbn (Nbs1)PrkdcRad50Rad51Rad52Rpa1Tp53bp1Xrcc2Xrcc6
Other DNA Repair Genes
AtrxBard1Bcl3Chek2FancaFancd2FancgGadd45aGadd45gMgmt (Agt)PolhPoliPttg1Rad1Rad17Rad18Rad21Rad51bRad51cRad9a (Rad9)Rev1Rnf8Smc1aSmc3Stt3aSumo1Topbp1Wrnip1
Apoptosis
AtmBard1BaxBcl3Brca1Cdkn1a (Cip1, Waf1)Chek2Csnk2a2LOC100909750 (Abl1)Ppp1r15a (Gadd34)PrkdcRad21Rad9a (Rad9)Sirt1 (QuantiNova Symbol: AABR07044925.1)Terf1Tp53 (p53)
Cell Cycle
AtmCdc25aCdc25cCdkn1a (Cip1, Waf1)Chek2Ddit3 (Gadd153, Chop)Mif (QuantiNova Symbol: LOC103694877)Ppm1d (Wip1)Ppp1r15a (Gadd34)Terf1Tp53 (p53)