Target List
Pro-Fibrotic
Acta2AgtCcl11 (Eotaxin)Ccl12Ccl3 (Mip-1a)Ccn2Grem1Il13Il13ra2Il4Il5Snai1 (Snail, Sna)
Anti-Fibrotic
Bmp7HgfIfngIl10Il13ra2
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents
Col1a2Col3a1
Extracellular Matrix (ECM) Remodeling Enzymes
LoxMmp1Mmp13Mmp14Mmp2Mmp3Mmp8Mmp9Plat (tPA)Plau (UPAM)PlgSerpina1Serpine1 (Pai-1)Serpinh1 (Hsp47)Timp1Timp2Timp3Timp4
Cell Adhesion Molecules
Itga1Itga2Itga3ItgavItgb1Itgb3Itgb5Itgb6Itgb8
Inflammatory Cytokines & Chemokines
Ccl11 (Eotaxin)Ccl12Ccl3 (Mip-1a)Ccr7Cxcr4IfngIl10Il13Il13ra2Il1aIl1bIl4Il5IlkLOC103694380 (Tnf)
Growth Factors
AgtCcn2Edn1EgfHgfPdgfaPdgfbVegfa
Signal Transduction
TGFβ Superfamily Members
Bmp7Cav1DcnEng (Evi-1)Grem1InhbeLtbp1Smad2Smad3Smad4Smad6Smad7Tgfb1Tgfb2Tgfb3Tgfbr1 (Alk5)Tgfbr2Tgif1Thbs1 (TSP-1, Tsp1)Thbs2
Transcription Factors
CebpbJunMycNfkb1Sp1Stat1Stat6
Epithelial-to-Mesenchymal Transition (EMT)
Akt1Bmp7Col1a2Col3a1IlkItgavItgb1Mmp2Mmp3Mmp9Serpine1 (Pai-1)Smad2Snai1 (Snail, Sna)Tgfb1Tgfb2Tgfb3Timp1
Other Fibrosis Genes
Bcl2Faslg