Target List
Toll-Like Receptor (TLR) Signaling
Toll-Like Receptors & Cofactors
Cd14CtskTlr1Tlr2Tlr4Tlr5Tlr6Tlr9
MYD88-Dependent
FaddIrak1Irak3Irf5Irf7LOC100910771 (Map3k7)Myd88Tab1TirapTlr1Tlr2Tlr4Tlr5Tlr6Tlr9TollipTraf6
TICAM1 (TRIF)-Dependent (MYD88-Independent) Signaling
Irf5Irf7LOC100910771 (Map3k7)Ripk1Tab1Ticam2 (Tram)Tlr4Traf6
Other Toll-Like Receptor Signaling Genes
Akt1Casp8 (Flice)LbpPik3ca (p110-alpha)Pik3r1 (PI3KA)Pstpip1Rac1
NOD-Like Receptor (NLR) Signaling
NOD-Like Receptors
Naip6 (QuantiNova Symbol: AC135826.1)Nlrc4 (Ipaf)Nlrp1a (Nalp1)Nlrp3Nod2
Inflammasomes
Casp1 (Ice)Naip6 (QuantiNova Symbol: AC135826.1)Nlrc4 (Ipaf)Nlrp1a (Nalp1)Nlrp3Pycard (Tms1, Asc)
Regulation of NOD-like Receptor (NLR) Signaling
Birc3 (c-IAP1)Card6Card9Casp8 (Flice)Hsp90aa1LOC103694380 (Tnf)MefvRipk2Sugt1Xiap
Other Bacterial Pattern Recognition Receptors (PRRs)
ApcsCrpDmbt1 (QuantiNova Symbol: AABR07005821.1)Zbp1
Signaling Downstream of Antibacterial Responses
NFκB Signaling
Bcl10Chuk (Ikbka, Ikka)Ikbkb (IKK2)Nfkb1Nfkbia (Iκbα, Mad3)RelaTnfrsf1a (Tnfr1)
ERK1 / ERK2 Signaling
JunMap2k1 (MEK1)Mapk1 (Erk2)Mapk3 (ERK1)
JNK / p38 Signaling
JunMap2k3 (Mek3)Map2k4 (Mkk4, Jnkk1)Mapk14 (p38alpha)Mapk8 (Jnk1)
Apoptosis
Akt1Birc3 (c-IAP1)Card6Card9Casp1 (Ice)Casp8 (Flice)Cd14FaddIfnb1Ikbkb (IKK2)Il12aIl12bIl1bIl6Irak1JunLOC100910771 (Map3k7)LOC103694380 (Tnf)Mapk1 (Erk2)Mapk8 (Jnk1)MpoNfkb1Nfkbia (Iκbα, Mad3)Pik3ca (p110-alpha)Prdx2Pycard (Tms1, Asc)Rac1Ripk1Ripk2Tnfrsf1a (Tnfr1)Traf6
Inflammatory Response
Akt1ApcsCcl3 (Mip-1a)Ccl5 (Rantes)Cd14CrpCxcl1Cxcl3Il1bIl6LbpLOC103694380 (Tnf)Lyz2MefvMyd88Nfkb1Nlrc4 (Ipaf)Nlrp3Rac1RelaRipk2Slc11a1Ticam2 (Tram)TirapTlr1Tlr2Tlr4Tlr5Tlr6Tlr9Tnfrsf1a (Tnfr1)Tollip
Cytokines & Chemokines
Ccl3 (Mip-1a)Ccl4 (Mip-1b)Ccl5 (Rantes)Cxcl1Cxcl3Ifnb1Il12aIl12bIl18Il1bIl6
Antimicrobial Peptides
BpiCampCtsgLcn2 (Ngal)Lyz2MpoPrtn3Slpi