Target List
TGFβ Signaling
ATF4CDKN1B (P27KIP1)EMP1GADD45BHERPUD1IFRD1MYCTNFSF10 (TRAIL)
WNT Signaling
AXIN2CCN4CCND1CCND2DAB2FOSL1 (FRA-1)MMP7MYCPPARD
NFκB Signaling
BCL2A1 (BFL1)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BIRC3 (c-IAP2)CCL5 (RANTES)CSF1 (MCSF)ICAM1IFNGSTAT1TNF
JAK / STAT Signaling
JAK1 & JAK2 / STAT1-Induced
IRF1
STAT3-Induced
BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)CCND1CEBPDLRG1MCL1SOCS3
STAT5-Induced
BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)CCND1SOCS3
JAK1 & JAK3 / STAT6-Induced
FCER2
JAK1 & JAK3 / STAT6 Responsive
GATA3
p53 Signaling
BAXBBC3 (PUMA)BTG2CDKN1A (p21CIP1, WAF1)EGFR (ERBB1)FASGADD45APCNARB1
Notch Signaling
HES1HES5HEY1HEY2HEYLID1JAG1LFNGNOTCH1
Hedgehog Signaling
BCL2BMP2BMP4PTCH1WNT1WNT2BWNT3AWNT5AWNT6
PPAR Signaling
ACSL3ACSL4ACSL5CPT2FABP1OLR1SLC27A4SORBS1
Oxidative Stress
FTH1GCLCGCLMGSRHMOX1NQO1SQSTM1TXNTXNRD1
Hypoxia Signaling
ADMARNTCA9EPOHMOX1LDHASERPINE1 (PAI-1)SLC2A1VEGFA