Target List
Pluripotency Maintenance Pathway
Cell Surface Receptors
IL6ST (GP130)LIFR
Transcription Factors
STAT3
Fibroblast Growth Factor (FGF) Signaling
Fibroblast Growth Factor Receptors
FGFR1FGFR2FGFR3FGFR4
Transcription Factors
CDX2
Hedgehog Signaling
Receptors & Co-Receptors
DISP3PTCH1SMO
Transcription Factors & Cofactors
GLI1GLI2GLI3SUFU
Notch Signaling
Receptors & Co-Receptors
NCSTNNOTCH1NOTCH2NOTCH3NOTCH4PSEN1PSEN2PSENEN (PEN2)
Transcription Factors
RBPJL
TGFβ / BMP Signaling
Receptors & Co-Receptors
ACVR1 (ALK2)ACVR1BACVR1CACVR2AACVR2BACVRL1 (ALK1)AMHR2BMPR1A (ALK3)BMPR1B (ALK6)BMPR2ENG (EVI-1)LTBP1LTBP2LTBP3LTBP4RGMATGFBR1 (ALK5)TGFBR2TGFBR3TGFBRAP1
Transcription Factors & Cofactors
CREBBP (CBP)E2F5EP300RBL1RBL2SMAD1 (MADH1)SMAD2 (MADH2)SMAD3 (MADH3)SMAD4 (MADH4)SMAD5 (MADH5)SMAD6SMAD7SMAD9SP1ZEB2
WNT Signaling
Frizzled Family Members & Other WNT Receptors
FZD1FZD2FZD3FZD4FZD5FZD6FZD7FZD8FZD9LRP5LRP6VANGL2
Transcription Factors & Cofactors
BCL9BCL9LCTNNB1LEF1NFAT5NFATC1NFATC2NFATC3NFATC4 (NFAT3)PYGO2TCF7TCF7L1TCF7L2