Target List
Regulation of Adipogenesis
Adipokines
ADIGADIPOQ (ACRP30)CFDLEP (Leptin)RETN
Hormones
AGTANGPT2
Lipases
LIPELPL
PPARγ Targets
ADIPOQ (ACRP30)AGTCEBPACFDFABP4FASNIRS2KLF15LIPELPLPPARGPPARGC1A (PGC-1α)RETNSIRT3SLC2A4 (GLUT4)SREBF1
Adipogenesis Regulation
Pro-Adipogenesis
ACACBAXIN1CCND1CDK4CEBPBCEBPDDKK1E2F1FABP4FASNFGF1FGF2 (BFGF)IRS2JUNLMNALPLPPARGRXRASFRP1SFRP5SLC2A4 (GLUT4)WNT5B
Anti-Adipogenesis
ADRB2CDKN1A (p21CIP1, WAF1)CDKN1B (P27KIP1)DDIT3 (GADD153, CHOP)DLK1FOXO1HES1LRP5NCOR2RUNX1T1SHHSIRT1SIRT2TAZTCF7L2TSC22D3VDRWNT1WNT3A
Pro-White Adipose Tissue
BMP2BMP4CEBPAEGR2FGF10KLF15KLF4SREBF1
Anti-White Adipose Tissue
GATA2GATA3KLF2KLF3
Pro-Brown Adipose Tissue
BMP7CREB1DIO2FOXC2INSRIRS1MAPK14 (p38ALPHA)NRF1PPARAPPARDPPARGC1A (PGC-1α)PPARGC1B (PGC-1β)PRDM16SIRT3SRCUCP1WNT5A
Anti-Brown Adipose Tissue
NCOA2NR0B2NR1H3RB1TWIST1WNT10B