Target List
Parkin Complex
HSPA4 (HSP70)PARK7STUB1
Parkin Substrate
ATXN2ATXN3GPR37SYT11
Cell Adhesion Molecules
APCAPPCDH8FN1NFASCNRXN3PTENTPBG
Ubiquitination
CDC27CUL2FBXO9LRRK2PAN2PRKNPINK1SKP1STUB1UBBUBA1UBE2IUBE2KUBE2L3UCHL1USP34
Inflammation
FN1PRDX2YWHAZ
Apoptosis
Pro-Apoptotic
APCAPPCASP1 (ICE)CASP3CASP8 (FLICE)CASP9CUL2MAPK9 (JNK2)PSEN2PTEN
Anti-Apoptotic
APCBDNFCASP3CASP9NEFLNR4A2 (NURR1)OPA1PPIDPRDX2PSEN2PTENSLC25A4SNCATCF7L2UBBYWHAZ
Mitochondrial Genes
CASP3CASP7CASP8 (FLICE)HSPA4 (HSP70)LRRK2NEFLOPA1PARK7PINK1PTENSLC25A4SNCATHUCHL1VAMP1VDAC3YWHAZ
Synaptic Vesicles
LRRK2SEPT5SV2BSYNGR3SYT1SYT11TH
Signal Transduction
Dopaminergic Signaling
NSG1DDCDRD2HTR2ANR4A2 (NURR1)PRKNPARK7PINK1SEPT5SLC6A3 (DAT)SNCATH
GABAergic Signaling
DRD2GABBR2
MAP Kinase Signaling
APCFGF13MAPK9 (JNK2)PRDX2RGS4
Notch Signaling
APPPSEN2SPEN
Cytoskeleton Regulators
APCCDC42MAPTNEFLPRKN
Ion Transport
ATP2B2CADPSCXXC1DRD2EGLN1GBE1GRIA3HTR2AKCNJ6NSFPSEN2S100BSRSF7SLIT1SNCAVDAC3
Transporters
ATP2B2
Channels & Transporters
GRIA3SLC18A2 (VMAT2)SLC6A3 (DAT)SLC25A4SV2BSYT1SYT11VDAC3
Other Parkinson's Disease Genes
ALDH1A1 (RALDH1)BASP1CHGBDLK1NCOA1NTRK2RTN1