Target List
Upstream Hippo Signaling Regulators
ACTG1AMOTAMOTL1AMOTL2CASP3CRB1CRB2CRB3CSNK1DCSNK1EDCHS1DCHS2DIAPH2DLG1DVL2FAT1FAT2FAT3FAT4FJX1AJUBALIMD1LIX1LLLGL1LLGL2LPPNF2RASSF2RASSF4SCRIBWTIPWWC1ZDHHC18
Hippo Core Kinase Complex
LATS2MOB1BMOB1ASAV1STK3STK4TAZYAP1MST1WWTR1
Downstream Mediators of Hippo Signaling
HIPK2MAPK10 (JNK3)MEIS1PRKCIPRKCZSMAD1 (MADH1)TEAD1TEAD2TEAD3TEAD4TP63TSHZ1TSHZ2TSHZ3WNT1
Hippo Signaling Target Genes
CASP3CCNE1CCNE2MYCPPP2CBPPP2R1APPP2R2DPTPN14RERE
Contact Inhibition
NF2TAZYAP1
Cell Polarity
CRB1CRB2CRB3DCHS1DCHS2FAT1FAT2FAT3FAT4LATS1LATS2MST1SCRIBSTK3STK4GPC5HMCN1POTEFTAOK1TAOK2TAOK3TJP1TJP2MPDZMPP5NPHP4PARD3PARD6G
Scaffolding Proteins
YWHABYWHAEYWHAQ (14-3-3θ)YWHAZ