Target List
p53 Activation
AtmAtrBrca1Cdkn1a (Cip1, Waf1)Cdkn2a (INK4A, p16, p19ARF)Chek2Ep300 (QuantiNova Symbol: AABR07058539.1)Foxo3Mdm2Msh2Pmaip1 (NoxA)Sirt1 (QuantiNova Symbol: AABR07044925.1)Tp63Tp73
p53 Regulators & Interactors
Cdkn2a (INK4A, p16, p19ARF)Dnmt1Hdac1Mdm2Mdm4Sirt1 (QuantiNova Symbol: AABR07044925.1)Tp53bp2Tp63Tp73
p53 Targets
Apoptosis
Apaf1BaxBtg2Casp9EgfrEsr1 (Erα)FasLOC103694380 (Tnf)Pmaip1 (NoxA)PrkcaSfn (14-3-3σ)Tnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tp53 (p53)Tp73Zmat3
Cell Cycle
Ccng1Cdc25aCdc25cCdkn1a (Cip1, Waf1)E2f1E2f3Mdm2MycPpm1d (Wip1)Rb1RprmSesn2
DNA Damage & Repair
Brca1Btg2EgfrGadd45aPcnaPttg1
Angiogenesis
Il6PtenSerpinb5 (Maspin)
Responses Downstream of p53 Signaling
Apoptosis
Apaf1Bag1Bcl2Bcl3BidBirc5Bnip3BokCasp2Casp9Cul9Dapk1FaddFaslgIgf1rNf1Nfkb1RelaWt1
Cell Cycle
Ccnb1Ccne1Ccng1CcnhCdk1Cdk4Prc1
DNA Damage & Repair
Apex1BokBrca2Ercc1Lig4Mlh1Xrcc4Xrcc5
Transcription Factors & Regulators
Bcl3Brca2Egr1Hif1aJunMyod1Nfkb1RelaStat1
Other Responses Downstream of p53 Signaling
KrasStt3a