Target List
TNF Superfamily Members
Induction of Apoptosis
FaslgLta (Tnfb)Tnfsf10 (Trail)Tnfsf14
Caspase Activation
Tnfsf15
Caspase Inhibition
Tnfsf14
Anti-Apoptotic
Cd40lgLOC103694380 (Tnf)Tnfsf18
Other Apoptosis Genes
Cd70 (Tnfsf7)Tnfsf9
Inflammatory Response
Cd40lgLOC103694380 (Tnf)
NFκB Signaling
FaslgLOC103694380 (Tnf)Tnfsf10 (Trail)Tnfsf14Tnfsf15
Other TNF Superfamily Members
LOC103689974 (Tnfsf11)LOC103694381 (Ltb)Pglyrp1Psmg2Tnfsf12Tnfsf13Tnfsf4 (Ox40l)
TNF Receptor Superfamily Members
Induction of Apoptosis
Cd27 (Tnfrsf7)FasTnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tnfrsf25 (Dr3)Tnfrsf9Tradd
Caspase Activation
Tnfrsf10b (QuantiNova Symbol: AABR07018323.1)
Caspase Inhibition
Cd27 (Tnfrsf7)
Anti-Apoptotic
Cd27 (Tnfrsf7)Fas
Other Apoptosis Genes
Cd40LtbrNgfrTnfrsf11b (Opg)Tnfrsf12aTnfrsf14Tnfrsf1a (Tnfr1)Tnfrsf1bTnfrsf21
Inflammatory Response
Cd40Tnfrsf1a (Tnfr1)
NFκB Signaling
Cd27 (Tnfrsf7)Cd40LtbrTnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tnfrsf1a (Tnfr1)Tradd
JNK / p38 Signaling
Cd27 (Tnfrsf7)
Other TNF Receptor Superfamily Members
Relt (Tnfrsf19l)Tnfrsf13cTnfrsf17Tnfrsf4 (Ox40)Tnfrsf8
TNF Receptor Superfamily Cofactors
Bex3Faf1Fbf1Ripk1Tab1
TNFR1 Signaling
Induction of Apoptosis
Casp3FaddTradd
Caspases
Casp2Casp3Casp8 (Flice)
Anti-Apoptotic
Bag4Casp2LOC103694380 (Tnf)
Other Apoptosis Genes
DffaPak1Tnfrsf1a (Tnfr1)Traf2
Inflammatory Response
LOC103694380 (Tnf)Tnfrsf1a (Tnfr1)
NFκB Signaling
Casp8 (Flice)FaddLOC103694380 (Tnf)Tnfrsf1a (Tnfr1)Tradd
JNK / p38 Signaling
Map2k4 (Mkk4, Jnkk1)Mapk8 (Jnk1)Pak1
Transcriptional Regulation
JunLOC103694380 (Tnf)Parp1 (Adprt1)Rb1Tnfrsf1a (Tnfr1)
Other TNFR1 Signaling Genes
Agfg1 (Hrb)ArhgdibCadLmnaLmnb1LOC100910732 (Pak2)LOC100910771 (Map3k7)MaddMap3k1 (Mekk1)PrkdcSptan1
TNFR2 Signaling
Induction of Apoptosis
IkbkgLta (Tnfb)Traf3
Anti-Apoptotic
Nfkb1
Other Apoptosis Genes
Nfkbia (Iκbα, Mad3)Tnfrsf1bTraf2Traf4Traf6Traf7
Inflammatory Response
Nfkb1
NFκB Signaling
Chuk (Ikbka, Ikka)Ikbkb (IKK2)IkbkgNfkbia (Iκbα, Mad3)Tank
Transcriptional Regulation
Ikbkb (IKK2)IkbkgNfkb1Nfkbia (Iκbα, Mad3)
Other TNFR2 Signaling Genes
Agfg1 (Hrb)Dusp1Elp1Map3k1 (Mekk1)Map3k14
Death Receptor Signaling
Apaf1Bcl2BidCflar (Casper)Cycs