Target List
Genomic Instability
Bub1bMrpl43PolrmtTfamTfb1mTfb2mZmpste24
Telomere Attrition
Pot1Rap1aTerf1Terf2Tinf2Tpp1
Mitochondrial Dysfunction
Mrpl43Ndufb11PolrmtSirt3Sirt6TfamTfb1mTfb2m
Proteostasis
Arl6ip6Bub1bFoxo1Hsf1 (Tcf5)Jakmip3Rnf144bTxnipVps13c
Laminopathies
LmnaLmnb1Lmnb2Zmpste24
Neurodegeneration & Synaptic Transmission
Calb1GfapMbpScn2bSnap23 (QuantiNova Symbol: AABR07053516.1)
Epigenetic Alterations
Arid1aSirt3Sirt6
DNA Binding
Arid1aElp3Ep300 (QuantiNova Symbol: AABR07058539.1)Fbxl16Zbtb10Zfp9Zfr
RNA Binding
Elavl1Lsm5Zfr
Inflammatory Response
Angel2Anxa3Anxa5C1qaC1qbC1qcC1sC3C3ar1C4aC4bC5ar1 (Gpr77)Ccr1Cd14Cd163CfhCfhr1Cx3cl1Cxcl16Fcer1gFcgbpFcgr1aFcgr2aFcgr2bGfapLtfLyzl1MbpPanx1S100a8S100a9Tlr2Tlr4Tmem135Tmem33Tollip
Apoptosis
Casp1 (Ice)CluEp300 (QuantiNova Symbol: AABR07058539.1)Pdcd6Tollip
Cellular Senescence
Cdkn1c (p57KIP2)Vwa5a (QuantiNova Symbol: LOC108348048)Wrn
Cell Cycle
Bub1bCdkn1c (p57KIP2)
Cytoskeleton Regulators
Col1a1Eml1
Oxidative Stress
Ep300 (QuantiNova Symbol: AABR07058539.1)
Transcriptional Regulation
Arid1aEp300 (QuantiNova Symbol: AABR07058539.1)Foxo1Hsf1 (Tcf5)Phf3Smad2