Target List
Apoptosis
Akt1Bcl2Bcl2l1 (Bcl-xl)Bcl2l1 (Bcl-xl)Bcl2l1 (Bcl-xl)Casp8 (Flice)Casp9Faslg
Necrosis
CyldGrb2MagParp2PvrTxnl4b
DNA Damage & Repair
AtmBrca1Cdkn1a (Cip1, Waf1)Ercc2 (Xpd)Mdm2Rad51
Mitochondrial Energy Metabolism
Arrdc3Asb1Cyb561d1Dnajb1Hspa1a (Hsp70-1)Slc25a25
Fatty Acid Metabolism (β-Oxidation)
AcadmAcadvlAcox1Cpt1aCpt1bCpt2
Oxidative Stress & Antioxidant Response
Akr1c2Fhl2GclmHmox1Ncoa7Nqo1Slc7a11
Heat Shock Response
Hsf1 (Tcf5)Hsp90b1Hspa4 (Hsp70)Hspa5 (Grp78)Hspb1 (Hsp27)Hspd1
Endoplasmic Reticulum Stress & Unfolded Protein Response
Adm2AsnsDnajb9Herpud1InhbeTrib3 (Skip3)Uhrf1
Cytochrome P450s & Phase I Drug Metabolism
Cyp1a1Cyp1a2Cyp2d4Cyp2e1Cyp3a18
Steatosis
Cd36 (QuantiNova Symbol: RGD1565355)Edn1FasnLplPparaScdSrebf1
Cholestasis
Abcb1a (Mdr1)Abcc2 (Cmoat, Mrp2)Abcc3 (Mlp2, Mrp3)Atp8b1Edn1PdynRdxSlc51a
Phospholipidosis
Asah1HpnLOC100909595 (Slc2a3)LOC299282 (QuantiNova Symbol: Serpina3n)LssTaglnWipi1
Immunotoxicity
Adh1F2 (Thrombin)HpxLyz2Metap2Mki67Nr5a2Trim10