Target List
Cell Fate Commitment
DKK1HES1HES5JAG1NODALNOTCH1NOTCH3PAX6RUNX2SOX9
Developmental Processes
Embryonic Development
DKK1EDN1EFNB1FOXC1FOXD3FOXF1HES1HES7MYF5NODALNOTCH1PBX1PCDH8PDGFRAPDGFRBRBPJTCF15VEGFAWNT4WNT5A
Muscle Development
EDN1EGR3FOXC1HBEGFHEY2IGFBP3JAG1MYF5NOTCH1PDGFBPDGFRBTNC
Epidermis Development
JAG1KRT14NOTCH1PTGS2 (COX2)SNAI1 (SNAIL)SOX9TCF15
Immune System Development
ID2JAG1JUNKITLG (SCF)KITLG (SCF)PBX1RUNX1 (AML1)SGPL1VEGFA
Nervous System Development
BDNFCCND2DKK1DTX1EFNA1EFNB1EGR3FABP7FOXC1HES1HES5HEY1HEY2HEYLID3ID4JAG1KALRNNESNODALNOTCH1NOTCH3PAX6PBX1RBPJRND1VEGFA
Vasculature Development
EDN1EFNA1FLT1 (VEGFR1)FOXC1FOXF1HEY2ID1JAG1JUNNODALNOTCH1RBPJRUNX1 (AML1)SGPL1VEGFA
Kidney Development
ADAMTS1BDNFFOXC1PBX1PDGFRBSGPL1
Other Developmental Processes
NRARPS1PR3
Signal Transduction
Notch Signaling
CREBBP (CBP)DTX1FOXC1HES1HES7HEY1HEY2HEYLJAG1LFNGNOTCH1NOTCH3RBPJRBPJLSNW1 (SKIIP)
WNT Signaling
CCND1DKK1FRZB (FRP-3)FZD5CCN4WNT4WNT5AWNT6
Apoptosis
ABL1BDNFFOXC1GADD45BID3IGFBP3JUNKALRNNOTCH1PTCRAPTGS2 (COX2)SGPL1SOCS3SOX9VEGFA
Cytokines
CX3CL1CXCL12 (SDF1)CXCL2 (GRO2, GROb, SCYB2)IL33NAMPT
Transcription Factors
CBFA2T3CLOCKCREBBP (CBP)EGR3FOXC1FOXD3FOXF1HEY1HEY2HEYLJUNMSCMYF5NOTCH1PAX6PBX1RBPJRBPJLRUNX1 (AML1)RUNX2SOX9TCF15
Other Notch Signaling Targets
FJX1GPSM2HSPB8MARK1RHOVTEC